1
PET Whole Body Biodistribution and Test Retest Bain Imaging Studies Using a Phosphodiesterase 4 Inhibitor (R)-[11C]Rolipram
Condition(s): Dosimetry; Healthy Last Updated: May 1, 2013Completed
467 Clinical Trials for: Phosphodiesterase 4 Inhibitors, Page 1 of 24
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2
A Proof-of-principle Study of Oral Treatment of Non-alcoholic Steatohepatitis With a Novel PDE4 Inhibitor ASP9831
Condition(s): Non-Alcoholic Steatohepatitis Last Updated: March 19, 2013Completed
3
Roflumilast and Cognition
Condition(s): Dementia Last Updated: November 8, 2011Recruiting
4
Topical Roflumilast in Adults With Atopic Dermatitis
Condition(s): Atopic Dermatitis Last Updated: May 14, 2013Recruiting
5
Efficacy and Safety of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 70 y) (APTA-2217-05)
Condition(s): Bronchial Asthma Last Updated: May 4, 2012Completed
6
Efficacy and Safety of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-06)
Condition(s): Chronic Obstructive Pulmonary Disease (COPD) Last Updated: May 4, 2012Completed
7
Long-term Study of Safety and Efficacy of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 71 y) (APTA-2217-07)
Condition(s): Bronchial Asthma Last Updated: May 4, 2012Completed
8
Long-term Study of Safety and Efficacy of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-08)
Condition(s): Chronic Obstructive Pulmonary Disease (COPD) Last Updated: May 4, 2012Completed
9
A Study to Evaluate the Efficacy After Allergen Challenge, Safety and Tolerability of Inhaled CHF6001 DPI in Asthmatics
Condition(s): Asthma Last Updated: May 8, 2013Completed
10
First Time in Human Study
Condition(s): Depressive Disorder and Anxiety Disorders; Depressive Disorder; Anxiety Disorders; Depressive Disorder, Major Last Updated: October 1, 2010Completed
11
Apremilast in the Treatment of Moderate to Severe Acne
Condition(s): Acne Last Updated: March 8, 2012Terminated
12
Safety Study of Clinical and Immune Effects of Phosphodiesterase 4 (PDE-4) Inhibitor in Cutaneous Lupus Patients
Condition(s): Discoid Lupus Erythematosus Last Updated: December 10, 2012Completed
13
Effects of ROFLUMILAST on Subclinical Atherosclerosis in Chronic Obstructive Pulmonary Disease (COPD)
Condition(s): Chronic Obstructive Pulmonary Disease and Allied Conditions Last Updated: June 27, 2012Recruiting
14
Efficacy and Safety of Oral Roflumilast Taken With Low Dose Inhaled Corticosteroids in Patients With Asthma (12 to 70 y) (BY217/M2-013)
Condition(s): Asthma Last Updated: May 4, 2012Completed
15
Efficacy and Safety of Roflumilast Taken in the Morning or Evening in Patients With Stable Asthma (12 to 70 y) (BY217/M2-015)
Condition(s): Asthma Last Updated: May 4, 2012Completed
16
Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease
Condition(s): Chronic Obstructive Pulmonary Disease Last Updated: May 9, 2012Not yet recruiting
17
Topical GW842470X In Adults Patients With Moderate Atopic Dermatitis
Condition(s): Atopic Dermatitis; Dermatitis, Atopic Last Updated: May 31, 2012Completed
18
Study of Apremilast in Atopic or Contact Dermatitis
Condition(s): Atopic Dermatitis; Allergic Contact Dermatitis Last Updated: November 23, 2010Completed
19
Safety, Tolerability and Efficacy of 28-day Inhaled CHF 6001 DPI in COPD Patients
Condition(s): COPD Last Updated: November 21, 2012Recruiting
20
Healthy Volunteer Positron Emission Tomography (PET) Brain Occupancy Study of a Phosphodiesterase 4 (PDE4) Inhibitor in Huntington's Disease
Condition(s): Huntington Disease Last Updated: May 17, 2012Completed
