The purpose of this study is to determine the effects of nefazedone on cocaine self-administration in depressed and non-depressed female cocaine users...
Date First Received: September 20, 1999
Last Updated: August 16, 2005
Verified by: National Institute on Drug Abuse (NIDA), December 1998
Clinical Trial Phase: Phase 2 | Start Date: December 1996
Overall Status: Completed
Estimated Enrollment: 0
Brief Summary
Official Title: “Effects of Nefazodone on Treatment of Female Cocaine Abusers”
Condition Keyword(s):
Intervention(s):
The purpose of this study is to determine the effects of nefazedone on cocaine self-administration in depressed and non-depressed female cocaine users.
Study Type: Interventional
Study Design: Treatment, Double-Blind, Placebo Control
Detailed Clinical Trial Description
This study evaluated the effect of nefazodone on reducing cocaine use and craving in both depressed and nondepressed women and if there was a greater effect in depressed women.
Intervention(s) in this Clinical Trial
- Drug: Nefazodone
Outcome Measures for this Clinical Trial
Primary Measures
- Craving
- Drug use
- Depression
- Life functioning
- HIV risk behaviors
Criteria for Participation in this Clinical Trial
Inclusion Criteria:
- Females, ages 18-55, minimum use of 8 days of the last 30, minimum of 8th grade education, current diagnosis of cocaine abuse/dependence
Exclusion Criteria:
- Unstable medical illness, dx of MR, OBS, bipolar
Gender Eligibility for this Clinical Trial: Female
Minimum Age for this Clinical Trial: 18 Years
Maximum Age for this Clinical Trial: 55 Years
Are Healthy Volunteers Accepted for this Clinical Trial?: No
Clinical Trial Sponsor Information
Lead Sponsor: National Institute on Drug Abuse (NIDA)
Overall Clinical Trial Officials and Contacts
Dorothy Hatsukami, Ph.D. Principal Investigator University of Minnesota
Additional Information
Information obtained from ClinicalTrials.gov on September 05, 2008
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00000286
Study ID Number: NIDA-09259-3
ClinicalTrials.gov Identifier: NCT00000286
Health Authority: United States: Federal Government
Clinical Trials Authorship and Review
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