To compare pyrimethamine and intravenous (IV) clindamycin vs. pyrimethamine and sulfonamides in the treatment of AIDS patients with central nervous system (CNS) Toxoplasma gondii...
Date First Received: November 2, 1999
Last Updated: June 23, 2005
Verified by: NIH AIDS Clinical Trials Information Service, June 1989
Clinical Trial Phase: N/A | Start Date:
Overall Status: Completed
Brief Summary
Official Title: “Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse”
Condition Keyword(s):
Intervention(s):
To compare pyrimethamine and intravenous (IV) clindamycin vs. pyrimethamine and sulfonamides in the treatment of AIDS patients with central nervous system (CNS) Toxoplasma gondii.
Study Type: Interventional
Study Design: Treatment, Dose Comparison
Intervention(s) in this Clinical Trial
- Drug: Pyrimethamine
- Drug: Clindamycin
Criteria for Participation in this Clinical Trial
Exclusion Criteria
Co-existing Condition:
Patients with the following conditions are excluded:
- Opportunistic infection (Pneumocystis carinii pneumonia (PCP), cryptococcal meningitis) or other conditions (brain abscess) which would make treatment results difficult to interpret due to concurrent infection, disease, or therapy.
- Patients with other opportunistic infections or brain diseases are excluded.
- Patients with AIDS and cerebral toxoplasmosis.
Gender Eligibility for this Clinical Trial: Both
Minimum Age for this Clinical Trial: 18 Years
Maximum Age for this Clinical Trial: N/A
Are Healthy Volunteers Accepted for this Clinical Trial?: No
Clinical Trial Sponsor Information
Lead Sponsor: Palo Alto Medical Foundation
Additional Information
Information obtained from ClinicalTrials.gov on October 07, 2008
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00002064
Study ID Number: 021A
ClinicalTrials.gov Identifier: NCT00002064
Health Authority: United States: Food and Drug Administration
Clinical Trials Authorship and Review
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