A study to compare pre-operative administration of rofecoxib versus post-operative administration of diclofenac or rofecoxib, respectively, in the treatment of post-operative pain after total knee joint replacement in patients with osteoarthritis of the knee...
Date First Received: August 30, 2005
Last Updated: November 30, 2006
Verified by: Merck, November 2006
Clinical Trial Phase: Phase 4 | Start Date: January 2004
Overall Status: Terminated
Estimated Enrollment: 150
Brief Summary
Official Title: “A Study to Compare Pre-Operative Administration of Rofecoxib Vs Post-Operative Administration of Diclofenac or Rofecoxib in the Treatment of Post-Operative Pain After Total Knee Joint Replacement in Patients With Osteoarthritis of the Knee.”
Condition Keyword(s):
Intervention(s):
A study to compare pre-operative administration of rofecoxib versus post-operative administration of diclofenac or rofecoxib, respectively, in the treatment of post-operative pain after total knee joint replacement in patients with osteoarthritis of the knee.
Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study
Outcome Measures for this Clinical Trial
Primary:
- Quantity of patient controlled
- Post-operative morphine administration
Criteria for Participation in this Clinical Trial
Inclusion Criteria:
- Males or females at least 18 years of age who have osteoarthritis of the knee and have undergone total knee joint replacement.
Clinical Trials Locations, Contact Details, and Sponsors
Lead Sponsor: Merck
Msd Sharp & Dohme Gmbh
Haar 85540 Germany
Overall Clinical Trial Officials and Contacts
Medical Monitor Study Director Merck
Additional Information
Information obtained from ClinicalTrials.gov on July 18, 2008
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00140920
Study ID Number: 2005_054
ClinicalTrials.gov Identifier: NCT00140920
Health Authority: Germany: Federal Institute for Drugs and Medical Devices
Clinical Trials Authorship and Review
Clinical Trials content is provided directly by the U.S. National Institutes of Health via ClinicalTrials.gov and is not reviewed separately by ClinicalTrialsFeeds.org. Every page of specific clinical trials information contains a unique identifier which can be used to find further details directly from the National Institutes of Health.
