To compare the efficacy and safety results of intravitreal bevacizumab alone with bevacizumab + triamcinolone acetonide in neovascular AMD...
Date First Received: August 30, 2006
Last Updated: June 25, 2008
Verified by: Shaheed Beheshti Medical University, June 2008
Clinical Trial Phase: Phase 3 | Start Date: November 2005
Overall Status: Active, not recruiting
Brief Summary
Condition Keyword(s):
Intervention(s):
To compare the efficacy and safety results of intravitreal bevacizumab alone with bevacizumab + triamcinolone acetonide in neovascular AMD.
Study Type: Interventional
Study Design: Treatment, Randomized, Single Blind (Subject), Active Control, Parallel Assignment, Safety/Efficacy Study
Intervention(s) in this Clinical Trial
- Drug: bevacizumab
- Injection of intravitreal bevacizumab
- Drug: bevacizumab + triamcinolone acetonide
- Injection of bevacizumab + triamcinolone acetonide
Arms, Groups and Cohorts in this Clinical Trial
- Active Comparator: 1
- Injection of intravitreal bevacizumab
- Active Comparator: 2
- Injection of bevacizumab + triamcinolone acetonide
Outcome Measures for this Clinical Trial
Primary Measures
- visual acuity
Secondary Measures
- central macular thickness
- leakage in fluorescein angiography
- intraocular pressure
- anterior chamber reaction
Criteria for Participation in this Clinical Trial
Inclusion Criteria:
- Cases of active neovascular AMD with visual acuity of 20/400- 20/40
Exclusion Criteria:
- History of glaucoma or ocular hypertension
- Disciform scar
Gender Eligibility for this Clinical Trial: Both
Minimum Age for this Clinical Trial: 50 Years
Maximum Age for this Clinical Trial: N/A
Are Healthy Volunteers Accepted for this Clinical Trial?: No
Clinical Trial Sponsor Information
Lead Sponsor: Shaheed Beheshti Medical University
Overall Clinical Trial Officials and Contacts
Hamid Ahmadieh, MD Principal Investigator Ophthalmic Research Center of Shaheed Beheshti Medical University
Additional Information
Information obtained from ClinicalTrials.gov on August 20, 2008
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00370370
Study ID Number: 8533
ClinicalTrials.gov Identifier: NCT00370370
Health Authority: Iran: Ethics Committee
Clinical Trials Authorship and Review
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