To understand if acarbose, an alpha-glucosidase inhibitor usually for treating diabetes, will further lower post meal glucose and inflammatory state when taking together with moderate amount of alcohol during meal tolerance test in subjects with impaired glucose tolerance or mild diabetes...
Date First Received: January 1, 2007
Last Updated: January 3, 2007
Verified by: Taichung Veterans General Hospital, January 2007
Clinical Trial Phase: N/A | Start Date: January 2007
Overall Status: Recruiting
Estimated Enrollment: 30
Brief Summary
Condition Keyword(s):
Intervention(s):
To understand if acarbose, an alpha-glucosidase inhibitor usually for treating diabetes, will further lower post meal glucose and inflammatory state when taking together with moderate amount of alcohol during meal tolerance test in subjects with impaired glucose tolerance or mild diabetes.
Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Placebo Control, Single Group Assignment, Efficacy Study
Intervention(s) in this Clinical Trial
- Drug: Acarbose
Outcome Measures for this Clinical Trial
Primary Measures
- Postprandial hyperglycemia
Secondary Measures
- Postprandial inflammatory responses
- Postprandial oxidative stress
Criteria for Participation in this Clinical Trial
Inclusion Criteria:
- Subjects with mild diabetes without prior medications or impaired glucose tolerance
Exclusion Criteria:
- Pregnancy
- Recent major cardiac, renal and hepatic disease
- Intolerance to alcohol
- Allergy to acarbose treatment
Gender Eligibility for this Clinical Trial: Both
Minimum Age for this Clinical Trial: 25 Years
Maximum Age for this Clinical Trial: 75 Years
Are Healthy Volunteers Accepted for this Clinical Trial?: No
Clinical Trial Sponsor Information
Lead Sponsor: Taichung Veterans General Hospital
Overall Clinical Trial Officials and Contacts
Wayne H Sheu, MD, PhD Principal Investigator Taichung Veterans General Hospital
Overall Contact: I Te Lee, MD, MS 886-4-23592525 itlee@vghtc.gov.tw
Additional Information
Information obtained from ClinicalTrials.gov on August 29, 2008
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00417950
Study ID Number: 950801/C06138
ClinicalTrials.gov Identifier: NCT00417950
Health Authority: Taiwan: Department of Health
Clinical Trials Authorship and Review
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