Official Title: “A Single Dose Patient Preference Study Comparison in Patients With Open-Angle Glaucoma or Ocular Hypertension”

Patients will receive a single drop of two test articles and assess their comfort

Study Type: Interventional

Study Design: Treatment, Randomized, Double Blind (Subject, Caregiver, Investigator), Active Control, Crossover Assignment, Safety Study

Study Primary Completion Date: March 2008

Intervention(s) in this Clinical Trial

• Drug: AL-3862 + Timolol
  • Dosage of drug
• Drug: Timolol
  • Timolol drops as needed

Arms, Groups and Cohorts in this Clinical Trial

• Active Comparator: 1
• Experimental: 2

Primary Measures

• Patient Preference
  • Time Frame: 2 min
    Safety Issue?: No

Secondary Measures

• Comfort/discomfort of medication after dosing with one drop
  • Time Frame: 2
    Safety Issue?: No

Inclusion Criteria:

• Glaucoma or ocular hypertension
• No corticosteroid use within 30 days
• No antihistamine or analgesic drug use
• No artificial tear use within 3 days
• No concurrent conjunctivitis, keratitis, scleritis or uveitis

Exclusion Criteria:

• History of bronchial asthma or severe chronic obstructive pulmonary disease

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 18 Years

Maximum Age for this Clinical Trial: N/A

Are Healthy Volunteers Accepted for this Clinical Trial?: No

Lead Sponsor: Alcon Research

Information obtained from ClinicalTrials.gov on September 05, 2008

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00576342

Study ID Number: C-07-47

ClinicalTrials.gov Identifier: NCT00576342

Health Authority: United States: Food and Drug Administration