Official Title: “The Effect of Clopidogrel on Coated-Platelets in Patients Undergoing Cardiac Catheterization”

This study will explore the effect of clopidogrel on coated-platelets in patients who are given an loading dose before diagnostic catheterization or percutaneous coronary intervention. We hypothesis that clopidogrel will reduce the percentage of platelets that are coated and therefore more hypercoagulable.

Study Type: Interventional

Study Design: Basic Science, Open Label, Single Group Assignment

Study Primary Completion Date: June 2008

Intervention(s) in this Clinical Trial

• Drug: Clopidogrel
  • 300 mg loading dose

Arms, Groups and Cohorts in this Clinical Trial

• Experimental: 1

Primary Measures

• Change in the percentage of coated platelets
  • Time Frame: Within 24 hours
    Safety Issue?: No

Inclusion Criteria:

• Patients given clopidogrel loading dose before scheduled catheterization or percutaneous intervention

Exclusion Criteria:

• Acute coronary syndrome
• Unable to tolerate clopidogrel

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 18 Years

Maximum Age for this Clinical Trial: 65 Years

Are Healthy Volunteers Accepted for this Clinical Trial?: No

Lead Sponsor: University of Oklahoma

Overall Clinical Trial Officials and Contacts

Eliot Schechter, MD Principal Investigator University of Oklahoma  

Overall Contact: Eliot Schechter, MD 405-270-0501 eliot-schechter@ouhsc.edu

Information obtained from ClinicalTrials.gov on August 21, 2008

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00644657

Study ID Number: 13291

ClinicalTrials.gov Identifier: NCT00644657

Health Authority: United States: Institutional Review Board