C-Control: Efficacy and Safety of Therapy With Rosuvastatin in Statin-Naive and in Statin-Switched Patients

The study explores efficacy and safety of the lipid-lowering therapy with CRESTOR in statin-naive patients and in patients with previously unsuccessful statin therapy. This study was designed to investigate the dynamic of the lipid parameters and therapy tolerability during 8-10 weeks treatment with...

Date First Received: May 29, 2008

Last Updated: June 2, 2008

Verified by: AstraZeneca, May 2008

Clinical Trial Phase: N/A | Start Date: February 2007

Overall Status: Completed

Estimated Enrollment: 3392

Brief Summary

Official Title: “C-Control: Efficacy and Safety of Therapy With Rosuvastatin in Statin-Naive and in Statin-Switched Patients”

Condition Keyword(s):

The study explores efficacy and safety of the lipid-lowering therapy with CRESTOR in statin-naive patients and in patients with previously unsuccessful statin therapy. This study was designed to investigate the dynamic of the lipid parameters and therapy tolerability during 8-10 weeks treatment with CRESTOR

Study Type: Observational

Study Design: Other, Prospective

Study Primary Completion Date: August 2007

Arms, Groups and Cohorts in this Clinical Trial

  • : Pt with hypercholesteremia
    • Patients treated with CRESTOR because of hypercholesteremia

Outcome Measures for this Clinical Trial

Primary Measures

  • LDL-Cholesterin, HDL-Cholesterin, Triglycerides, Total Cholesterin
    • Time Frame: 3 visits within 10 weeks
      Safety Issue?: No

Secondary Measures

  • Tolerability of CRESTOR-therapy
    • Time Frame: 3 visits within 10 weeks
      Safety Issue?: No

Criteria for Participation in this Clinical Trial

Inclusion Criteria:

  • Patients with hypercholesteremia who was never treated with statins before
  • Patient with hypercholesteremia who was treated with a statin (other then rosuvastatin) but because of its adverse effects/insufficient action was switched to therapy with CRESTOR

Exclusion Criteria:

  • None

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: N/A

Maximum Age for this Clinical Trial: N/A

Are Healthy Volunteers Accepted for this Clinical Trial?: No

Clinical Trial Sponsor Information

Lead Sponsor: AstraZeneca

Additional Information

Information obtained from ClinicalTrials.gov on September 05, 2008

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00688454

Study ID Number: NIS-CCH-CRE-2007/1

ClinicalTrials.gov Identifier: NCT00688454

Health Authority: Switzerland: Ethikkommision

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